Gene transcriptions/Elements/Metal responsives/Quiz

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Metal responsive elements is a lecture as part of the gene transcription series.

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Quiz[edit | edit source]


1 Yes or No, The metallothionein (MT) genes provide a good example of eucaryotic promoter architecture.


2 The portion of a promoter in which an metal responsive element is likely to be found is which of the following?

dispersed promoter
proximal promoter
downstream promoter
distal promoter
focused promoter
core promoter

3 Yes or No, MT genes specify the synthesis of low-molecular-weight metal-binding proteins.


4 Several promoter elements have been previously identified in eukaryotes, but those cannot account for transcription from most RNA polymerase II-transcribed

5 True or False, Some metal responsive elements are located in the dispersed promoter.


6 Which of the following is not a transcriptional characteristic of metal responsive elements?

located between nucleotides -8 and +2 relative to the transcriptional start site (+1)
in eukaryotes
TATA-less genes
a consensus sequence

7 Complete the text:

The metal ion

of metallothionens is conferred by a

sequence element called the

-responsive element

or TGC


8 Complete the text:

Match up the type of promoter or promoter element with each of the possibilities below:
TATA box - A
initiator element - B
enhancers and inhibitors - C
downstream elements - D
General transcription factor II D - E
ATA box - F
downstream core promoter

includes the transcription start site

proximal promoter

distal promoter

core promoter

usually 25 nucleotides upstream


9 Which of the following are phenomena associated with metal responsive elements?

transcription of A1BG
directs activator-dependent but TFIID-independent transcription
TATA box-less promoters
initiator element
mediator dependence
core promoter

10 True or False, Metal responsive elements are found in the promoter regions of at least 1% of human genes.


Hypotheses[edit | edit source]

  1. A1BG is not transcribed by a metal responsive element.

See also[edit | edit source]

External links[edit | edit source]

{{Anthropology resources}}

{{Medicine resources}}{{Phosphate biochemistry}}