Talk:Gene transcriptions/A1BG

Wow! and how is this best understood as a learning resource?

Wow! this is quite a fact-filled article. How can I best understand this as a learning resource? Is this an essay, lecture, course or some other approach to learning? Who is the target audience? What prerequisites, if any, do students need? Is this part of a larger curriculum, or does it stand by itself? How can students find this material? Is in linked or indexed in a course catalog, school, portal or other organizing structure? What course do students take next? What can students who complete this course do differently as a result of the course? Thanks for his contribution. --Lbeaumont (discuss • contribs) 12:41, 31 October 2018 (UTC)

Great questions! Thanks for stopping by and asking them! I will look at each to find some straight-forward ways to answer. --Marshallsumter (discuss • contribs) 17:21, 1 November 2018 (UTC)

How can I best understand this as a learning resource?

Gene transcription of human alpha-1-B glycoprotein is part of an ongoing original research project called the gene project. A recent proposal Gene expressions in human exploration beyond low earth orbits was peer-reviewed by Dr. Mark J. Shelhamer, Chief Scientist for the International Space Station, and approved as part of Phase I. The proposal did not receive funding from the Phase II review. The main hypothesis is that one or more genes are causing brain, muscle, and bone mass loss by astronauts and cosmonauts aboard the ISS after multi-month tours of duty.

A1BG (human alpha-1-B glycoprotein) is a test gene to determine how to affect its transcription through the 16 possible transcription paths. --Marshallsumter (discuss • contribs) 17:21, 1 November 2018 (UTC)

A template such as {{Original research}} could be attached. What do you think? --Marshallsumter (discuss • contribs) 18:40, 1 November 2018 (UTC)

Is this an essay, lecture, course or some other approach to learning?

It is included as a lecture in Gene transcriptions/Courses. --Marshallsumter (discuss • contribs) 19:05, 1 November 2018 (UTC)

Who is the target audience?

The people behind these hits who may be post-graduates:

1. 151 - 1571 hits for Gene transcriptions/Start sites /2018/09 from
2. 82 - 998 hits for Transcription start site /2014/01

1. 704 - 303 hits for Gene transcriptions/Core promoters /2018/09 from
2. 485 - 337 hits for Core promoter /2015/01, for example, and others interested in genetics. --Marshallsumter (discuss • contribs) 22:04, 1 November 2018 (UTC)

What prerequisites, if any, do students need?

Gene transcriptions/Courses#Prerequisites mentions some general ones.

Some of the specifics mentioned in Gene transcriptions/A1BG require extensive background or familiarity with laboratory techniques and equipment. --Marshallsumter (discuss • contribs) 22:04, 1 November 2018 (UTC)

Is this part of a larger curriculum, or does it stand by itself?

As the focus of an original research project it stands by itself, but it is part of a larger developing curriculum which includes Paleanthropology, Zoology, Botany and Biology from a molecular genetics perspective. For example, A1BG appears to only occur in mammals. --Marshallsumter (discuss • contribs) 22:04, 1 November 2018 (UTC)

How can students find this material?

The several courses are in the Category:Science courses and materials are in the {{Gene project}}, {{medicine resources}}, {{Phosphate biochemistry}} and {{Anthropology resources}}.

Is it linked or indexed in a course catalog, school, portal or other organizing structure?

Many of the links are in the Portal:Genetics, Portal:Anthropology, Portal:Biochemistry, Portal:Biology, Portal:Dentistry, Portal:Life Sciences and Portal:Medicine.

What course do students take next?

The Gene transcriptions/Courses allow the students to put together course resources they need to give themselves the education and development they want. If any want a specific training such as with high-tech lab equipment, these can be prepared or the student can create these, if we don't have them as yet. There is also the Genetics/Course. --Marshallsumter (discuss • contribs) 01:48, 2 November 2018 (UTC)

What can students who complete this course do differently as a result of the course?

Genetics research and development: specifically alter gene expression to eliminate unhealthy effects. Apolipoprotein E, for example, can and apparently does cause all the symptoms summarized as brain, muscle, and bone mass loss from lengthy exposure to microgravity or confined bed rest for months at a time. Altering this one gene's expression could make an astronaut's body behave as if it's on Earth in a one G environment even though the astronaut is working, exercising or resting on the ISS. --Marshallsumter (discuss • contribs) 02:00, 2 November 2018 (UTC)