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Progress and Prospects in Parkinson's Research/Symptoms/D

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The A-Z of Parkinson's Symptoms

D 

In process of being complied from Introduction_to_Parkinson's_Science/Q_Page_40
Delerium

Redirected to Cognitive Impairment ( To subpage for editing >> )

Cognitive impairment

Problems with mental processes such as thinking, learning and judging

See also Dementia

The folllowing references are relevant.

Goldman and Litvan (2011) Mild Cognitive Impairment in Parkinson’s Disease[1]

Litvan et al(2011) MDS Task Force on Mild Cognitive Impairment in Parkinson’s disease: Critical Review of PD-MCI[2]

Weintrub et al (2011) Neurodegeneration Across Stages of Cognitive Decline in Parkinson Disease [3]

Further Research

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Literature search:

Use the following links to query the PubMed, PubMed Central and Google Scholar databases using the Search terms:- Parkinson's_Disease Cognitive_Impairment.
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References

  1. ↑ Goldman, J.G. and Litvan, I.(2011) Full TextMinerva Med. 102 (6) 441 – 45>Mild Cognitive Impairment in Parkinson’s Diseasehttp://www.ncbi.nlm.nih.gov/pmc/articles/PMC3370887/
  2. ↑ Litvan, I.; D Aarsland, D.; Adler, C. H.; Goldman, J. G.; Kulisevsky, J.; Mollenhauer, B.; Rodriguez-Oroz, M. C.; AI Tröster, Al and D Weintraub, D. (2011) Full TextMov. Disord. 26 (10) 1814 – 1824. MDS Task Force on Mild Cognitive Impairment in Parkinson’s disease: Critical Review of PD-MCI http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3181006/
  3. ↑ Weintrub, Daniel; Doshi, Jimit;Koka, Deepth; Davatzikos, Christos; Diderowf, Andrew D.; Duda, John E.; Wolk, David, Moberg, Paul J.; Xie, Sharon X. and Clark, Christopher M.(2011) Full TextArch. Neurol. 68 (12) 1562 – 1568. Neurodegeneration Across Stages of Cognitive Decline in Parkinson Disease http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3290902/
Delusion

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Delusion

A fixed false belief that is resistant to reason or confrontation with actuality

The following references are relevant:-

Goldman (2011) New Thoughts on Thought Disorders in Parkinson's Disease: Review of Current Research Strategies and Challenges [1]

Fénelon et al (2012) Feeling of presence in Parkinson's disease [2]

Mack et al (2012) Prevalence of Psychotic Symptoms in a Community-Based Parkinson’s Disease Sample [3]

Further Research

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Literature search:

Use the following links to query the PubMed, PubMed Central and Google Scholar databases using the Search terms:- Parkinson's_Disease Delusion.
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References

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  1. ↑ Goldman, Jennifer G. (2011) Full Text J. Neurol. Neurosurg. Psychiatry. 82 (11) 1219 – 1224 New Thoughts on Thought Disorders in Parkinson's Disease: Review of Current Research Strategies and Challenges http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3049364/
  2. ↑ Fénelon, Gilles; Soulas, Thierry; De Langavant, Cleret, Laurent; Trinkler, Iris and Bachoud-Levi, Anne-Cathherine (2012) Full Text Feeling of presence in Parkinson's disease http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3382202/
  3. ↑ Mack, Joel; Rabins, Peter; Anderson, Karen; Goldstein, Susan; Grill, Stephen; Hirsch, Elaina S.; Lehmann, Susan; Little, John T.; Margolis, Russell L.; Palanci, Justin; Pontone, Gregory; Weiss, Howard; Williams, James R. and Marsh, Laura (2012) Full Text Prevalence of Psychotic Symptoms in a Community-Based Parkinson’s Disease Sample http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3168582/
Dementia

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Dementia

Abnormal progressive decline in cognitive function

See also Cognitive Impairment

The following references are relevant.

Leverenz et al, (2009) Cognitive Impairment and Dementia in Patients with Parkinson Disease [1]

Johnson and Galvin (2011) Longitudinal Changes in Cognition in Parkinson's Disease with and without Dementia [2]

Weintraub et al (2011) Neurodegeneration Across Stages of Cognitive Decline in Parkinson Disease [3]

Further Research

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Literature search:

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References

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  1. ↑ Leverenz, James B.; Quinn, Joseph F.; Zabetian, Cyrus;Zhang, Jing; Montine, Kathleen S. and Montine, Thomas J. (date) Full TextCurr. Top Med. Chem. 9 (10) 903 – 912. Cognitive Impairment and Dementia in Patients with Parkinson Disease http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2804995/
  2. ↑ Johnson, David K.; and Galvin, James E. (2011) Full Text Dement. Geriatr. Cogn. Disord. 31 (2) 98 – 108. Longitudinal Changes in Cognition in Parkinson's Disease with and without Dementia http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3047760/
  3. ↑ Weintraub, Daniel; Doshi, Jimit; Koka, Deepthi’ Davatzikos, Christos; Siderowf, Andrew D.; Duda, John E.; Wolk, David A.; Moberg, Paul J.; Xie, Sharon X. and Clark, Christopher M. (2011) Full TextArch Neurol. 68 (12) 1562 – 1568. Neurodegeneration Across Stages of Cognitive Decline in Parkinson Disease http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3290902/
Disequilibrium

Redirected to Balance. ( To subpage for editing >> )

Balance

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Susceptibility to falls

Alternative terms

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Postural instability---Falls


The following references are relevant:-

King et al (2012) Do clinical scales of balance reflect turning abnormalities in people with Parkinson's disease? [1]

Duncan and Earhart (2012) Should One Measure Balance or Gait to Best Predict Falls among People with Parkinson Disease? [2]

Boonsinsukh et al (2012) A Cane Improves Postural Recovery From an Unpracticed Slip During Walking in People With Parkinson Disease [3]

Further Research

[edit | edit source]
Search the scientific literature

Literature search:

Use the following links to query the PubMed, PubMed Central and Google Scholar databases using the Search terms:- Parkinson's_Disease Balance.
This will list the latest papers on this topic. You are invited to update this page to reflect such recent results, pointing out their significance.
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References

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  1. ↑ King, L.A.; Mancini, M,; Priest, K.; Salarian, A.; Rodrigues-de-Paula, F. and Horak, F. (2012) Full Text J. Neurol. Phys. Ther. 36 (1) 25 – 31 Do clinical scales of balance reflect turning abnormalities in people with Parkinson's disease? http://www.ncbi.nlm.nih.gov/pubmed/22333919
  2. ↑ Duncan, Ryan P. And Earhart, Gammon M. (2012) Full Text Parkinsons Dis. 2012 923493 Should One Measure Balance or Gait to Best Predict Falls among People with Parkinson Disease? http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3503435/A
  3. ↑ Boonsinsukh, Rumpa; Saegsirsuwan, Vitoon; Carlson-Kuta, Patricia and Horak, Fay.B. (2012) Full Text Phys. Ther. 92 (9) 1117 – 1129 A Cane Improves Postural Recovery From an Unpracticed Slip During Walking in People With Parkinson Disease http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3432949/
Drooling

Redirected to Sialorrhoea ( To subpage for editing >> )

Sialorrhoea

Increased salivation

Alternative term:- Drooling

The following references are relevant:-

Kalf et al (2009) Prevalence and definition of drooling in Parkinson’s disease: a systematic review [1]

Bloem et al (2009) Debilitating consequences of drooling [2]

Kalf et al (2011) Diurnal and nocturnal drooling in Parkinson’s disease[3]

Further Research

Search the scientific literature - Sialorrhoea

Literature search:

Use the following links to query the PubMed, PubMed Central and Google Scholar databases using the Search terms:- Parkinson's_Disease Sialorrhoea.
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Search the scientific literature - Drooling

Literature search:

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References

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  1. ↑ Kalf, J.G.; de Swart, B.J.; Borm, G.F.; Bloem, B.R. and Munneke, M. (2009) Full TextJ. Neurol. 256 (9) 1391 – 1396Prevalence and definition of drooling in Parkinson’s disease: a systematic review http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2733191/
  2. ↑ Bloem, B,R,; Kalf, J.G.; van de Kerkhof, P.C.M. and Zwarts, M.J. (2009) Full TextJ. Neurol. 256 (8) 1382 – 1383Debilitating consequences of drooling http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2721959/
  3. ↑ Kalf, J.G.; Bloem, B.R. and Munneke, M. (2011) Full TextJ. Neurol. 259 (1) 119 – 123 Diurnal and nocturnal drooling in Parkinson’s disease http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3251785/
Drop Foot (locomotion defect whereby the heel of a foot is raised from the ground whle walking)

Redirected to Foot_Drop ( To subpage for editing >> )

Foot Drop or (Drop Foot)

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Locomotion defect whereby the heel of a foot is raised from the ground while walking

The following references are relevant:-

Belfiore and Campanella (1994) A clinical sign of Parkinson's disease: the absence of lateral foot drop [1]

Rogers et al (2011) Perturbations of ground support alter posture and locomotion coupling during step initiation in Parkinson's disease [2]

The following references are relevant:-

Further Research

[edit | edit source]
Search the scientific literature

Literature search:

Use the following links to query the PubMed, PubMed Central and Google Scholar databases using the Search terms:- Parkinson's_Disease Foot_Drop.
This will list the latest papers on this topic. You are invited to update this page to reflect such recent results, pointing out their significance.
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References

[edit | edit source]
  1. ↑ Belfiore, G. and Campanella, G. (1994) AbstractActa Neurol. (Napoli). 16 (5-6) 291 – 92 A clinical sign of Parkinson's disease: the absence of lateral foot drop http://www.ncbi.nlm.nih.gov/pubmed/7709801
  2. ↑ Rogers, M.W.; Hilliard, M.J.; Martinez, K.; Zhang, Y.;Simuni, T. and Mille, M.L. (2011) AbstractExp. Brain Res. 208 (4) 557 – 567 Perturbations of ground support alter posture and locomotion coupling during step initiation in Parkinson's disease. http://www.ncbi.nlm.nih.gov/pubmed/21153725a
Dysarthria (speech difficulties due to impairment of the muscles associated with vocalization)

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Dysarthria

Speech difficulties due to impairment of the muscles associated with vocalization.

The following references are relevant:-

MacPherson et al (2011) The Intonation-Syntax Interface in the Speech of Individuals with Parkinson’s Disease[1]

Skodda (2012) Effect of Deep Brain Stimulation on Speech Performance in Parkinson's Disease [2]

Walsh and Smith (2011) Linguistic Complexity, Speech Production, and Comprehension in Parkinson’s Disease: Behavioral and Physiological Indices [3]

Further Research

Search the scientific literature

Literature search:

Use the following links to query the PubMed, PubMed Central and Google Scholar databases using the Search terms:- Parkinson's_Disease Dysarthria.
This will list the latest papers on this topic. You are invited to update this page to reflect such recent results, pointing out their significance.
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References

  1. ↑ MacPherson, Megan K.; Huber, Jessica E. and Snow, David P.(2011) Full TextJ. Speech Lang. Hear. Res. 54 (1) 10 – 32 The Intonation-Syntax Interface in the Speech of Individuals with Parkinson’s Disease http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3441058/
  2. ↑ Skodda, Sabine (2012) Full TextParkinsons Dis. 2012: 85059 Effect of Deep Brain Stimulation on Speech Performance in Parkinson's Disease http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3512320/
  3. ↑ Walsh, Bridget and Smith, Anne (date) Full TextJ. Speech Lang. Hear. Res. 54 (3) 787 – 802 Linguistic Complexity, Speech Production, and Comprehension in Parkinson’s Disease: Behavioral and Physiological Indices http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3418801/
Dyskinesia (abnormality of muscle tone or movement)

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Dyskinesia

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Abnormality of muscle tone or movement.

The following references are relevant:-

Chung et al(2010) Objective Measurement of Dyskinesia in Parkinson Disease using a Force Plate [1]

Timbasco et al (2012) Clinical Aspects and Management of Levodopa-Induced Dyskinesia [2]

Espay et al (2012) “On” state freezing of gait in Parkinson disease -A paradoxical levodopa-induced complication [3]

Further Research

[edit | edit source]
Search the scientific literature

Literature search:

Use the following links to query the PubMed, PubMed Central and Google Scholar databases using the Search terms:- Parkinson's_Disease Dyskinesia.
This will list the latest papers on this topic. You are invited to update this page to reflect such recent results, pointing out their significance.
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References

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  1. ↑ Chung, Katherine A.; Lobb, Brenna M.; Nut, John G.; McNames, James and Horak, Fay (2010) Full Text Mov. Disord. 25 (5) 602 – 608 Objective Measurement of Dyskinesia in Parkinson Disease using a Force Plate http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3148105/
  2. ↑ Tambaco,Nicola; Smoni, Simone; Marsili, Erica; Sacchini, Elisa; Murasecco, Donatlla; Cardaioli, Gabriela, Ross, Aroldo an Clabresi, Paolo (2012) Full Text Parkinsons Dis. 2012: 745947. Clinical Aspects and Management of Levodopa-Induced Dyskinesia http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3372050/
  3. ↑ Espy, A.J.; Fasano, A.; van Nuenen, B.F.L.; Payne, M.M.; Snijders, A.H. and Bloem, B.R. (date) Full Text Neurology. 78 (7) 454 – 457. “On” state freezing of gait in Parkinson disease - A paradoxical levodopa-induced complication http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3466608/
Dysphagia (difficulty in swallowing)

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Dysphagia

Difficulty in swallowing.

See also Aphagia

Further Research

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Literature search:

Use the following links to query the PubMed, PubMed Central and Google Scholar databases using the Search terms:- Parkinson's_Disease Dysphagia.
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References

Dysphasia (difficulty in speech)

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Dysphasia

Difficulty in speaking

The following references are relevant:-

Colman et al (2011) Sentence Comprehension and Its Association with Executive Functions in Patients with Parkinson's Disease [1]

Baylor et al (2012) A qualitative study of interference with communicative participation across communication disorders in adults [2]

Fox et al(2012) LSVT LOUD and LSVT BIG: Behavioral Treatment Programs for Speech and Body Movement in Parkinson Disease [3]

Further Research

Search the scientific literature

Literature search:

Use the following links to query the PubMed, PubMed Central and Google Scholar databases using the Search terms:- Parkinson's_Disease Dysphasia.
This will list the latest papers on this topic. You are invited to update this page to reflect such recent results, pointing out their significance.
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References

  1. ↑ Colman, Katrien S.F.’ Koerts, Janneke; Stowe, Laurie A.; Leenders, Klaus L. and Basiaanse, Roelien (2011) Full Text Parkinsons Dis. 2011; 2011: 213983. Sentence Comprehension and Its Association with Executive Functions in Patients with Parkinson's Disease http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3202107/
  2. ↑ Baylor, Caroline; Burns, Michael; Eadie, Tanya; Britton, Deanna and Yorkston, Kathryn (2012) Full Text Am. J. Speech Lang Pathol. (20) (4) 269 – 287 A qualitative study of interference with communicative participation across communication disorders in adults http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3296484/
  3. ↑ Fox, Cynthis; Ebersbach, Georg; Ramig, Lorraine and Sapir, Shimon. (2012) Full Text Parkinsons Dis. 2012; 2012: 391946. LSVT LOUD and LSVT BIG: Behavioral Treatment Programs for Speech and Body Movement in Parkinson Disease http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3316992/
Dystonia (sustained muscle contractions causing twisting and repetitive movements or abnormal postures)

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Dystonia

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Sustained muscle contractions causing twisting and repetitive movements or abnormal postures.

Further Research

[edit | edit source]
Search the scientific literature

Literature search:

Use the following links to query the PubMed, PubMed Central and Google Scholar databases using the Search terms:- Parkinson's_Disease Dystonia.
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References

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< Back to Parkinson's Symptoms

Links to the symptoms of Parkinson's in alphabetical order:

A B C D E
F - G H I - L M - N O
P - Q R S T U - Z

(Click to go to table for editing)

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