Medical Research

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Medical disclaimer: This page is for educational and informational purposes only and may not be construed as medical advice. The information is not intended to replace medical advice offered by physicians. Please refer to the full text of the Wikiversity medical disclaimer.

This page lists current researches in developing cures and therapies for different pathologies.

The goal of this page is to be a tool see the current state of each research, how it's progressing or if it had failed.

Please help expand it!

Diabetes type 1[edit]

  • Cell Based Therapeutics[1]

Diabetes type 2[edit]

Kidney failure[edit]

  • Growing a Kidney In-Situ / De novo organogenesis[2]
  • Cell Transplantation[2]
  • Growing a Kidney In-Vitro[2]
  • Reseeding a Kidney: Decellularized Scaffolds[2]
  • Bioengineering a Kidney[2]
  • Bioartificial Renal Epithelial Cell System (BRECS)[2]
  • Implantable Renal Assist Device (iRAD)[2] / implantable bioartificial kidney (BAK)[3]

Cancer[edit]

Crohn's disease[edit]

Major Depressive Disorder[edit]

Inflammation-related depression[edit]

Studies shows for an elevated cytokines in depressed patients: IL-1β, IL-6, sIL-2R (soluble IL-2 receptors) and TNF-α [7] and those cytokines may reduce monoamine levels.[8]

Konsman present an important critical review paper on the subject.[9]

  • Anti-inflammatory Treatment[10]

See Also[edit]

References[edit]

  1. Zamboni, Fernanda; Collins, Maurice N. (2017-4). "Cell based therapeutics in type 1 diabetes mellitus". International Journal of Pharmaceutics. Elsevier. 521 (1–2): 346–356. doi:10.1016/j.ijpharm.2017.02.063. ISSN 0378-5173. PMID 28242376. Check date values in: |date= (help)
  2. 2.0 2.1 2.2 2.3 2.4 2.5 2.6 Kim, S; Fissell, WH; Humes, DH; Roy, S (2015). "Current strategies and challenges in engineering a bioartificial kidney". Frontiers in bioscience (Elite edition) (published 2015-01-01). 7: 215–228. ISSN 1945-0494. PMC 4383659. PMID 25553375.CS1 maint: PMC format (link)
  3. Humes, HD; Buffington, D; Westover, AJ; Roy, S; Fissell, WH (March 2014). "The bioartificial kidney: current status and future promise". Pediatric Nephrology. 29 (3): 343–351. doi:10.1007/s00467-013-2467-y. ISSN 0931-041X.
  4. Kast, RE; Altschuler, EL (Nov 2001). "Remission of Crohn's disease on bupropion". Gastroenterology. Elsevier. 121 (5): 1260–1261. doi:10.1053/gast.2001.29467. ISSN 0016-5085. PMID 11706830.
  5. Mosaic, LS. "Why a third of antidepressants are prescribed for something else". CNN. Retrieved 2019-07-06.
  6. Brustolim, D; Ribeiro-dos-Santos, R; Kast, RE; Altschuler, EL; Soares, MBP (Jun 2006). "A new chapter opens in anti-inflammatory treatments:The antidepressant bupropion lowers production of tumor necrosis factor-alpha and interferon-gamma in mice". International Immunopharmacology. Elsevier. 6 (6): 903–907. doi:10.1016/j.intimp.2005.12.007. ISSN 1567-5769. PMID 16644475.
  7. Liu, Yang; Ho, Roger Chun-Man; Mak, Anselm (2012-8). "Interleukin (IL)-6, tumour necrosis factor alpha (TNF-α) and soluble interleukin-2 receptors (sIL-2R) are elevated in patients with major depressive disorder: a meta-analysis and meta-regression". Journal of Affective Disorders. 139 (3): 230–239. doi:10.1016/j.jad.2011.08.003. ISSN 1573-2517. PMID 21872339. Check date values in: |date= (help)
  8. Yang, Longfei; Zhao, Yinghao; Wang, Yicun; Liu, Lei; Zhang, Xingyi; Li, Bingjin; Cui, Ranji (2015-08-31). "The Effects of Psychological Stress on Depression" (PDF). Current Neuropharmacology. 13 (4): 494–504. doi:10.2174/1570159x1304150831150507. PMC 4790405. PMID 26412069.CS1 maint: PMC format (link)
  9. Konsman, JP (2019-02-14). "Inflammation and Depression: A Nervous Plea for Psychiatry to Not Become Immune to Interpretation". Pharmaceuticals. 12 (1). doi:10.3390/ph12010029. ISSN 1424-8247. PMC 6469164. PMID 30769887.
  10. Kopschina Feltes, Paula; Doorduin, Janine; Klein, Hans C; Juárez-Orozco, Luis Eduardo; Dierckx, Rudi AJO; Moriguchi-Jeckel, Cristina M; de Vries, Erik FJ (2017-9). "Anti-inflammatory treatment for major depressive disorder: implications for patients with an elevated immune profile and non-responders to standard antidepressant therapy". Journal of Psychopharmacology (Oxford, England). 31 (9): 1149–1165. doi:10.1177/0269881117711708. ISSN 0269-8811. PMC 5606303. PMID 28653857. Check date values in: |date= (help)