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Drug discovery

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Educational level: this is a research resource.

Medical disclaimer: This page is for educational and informational purposes only and may not be construed as medical advice. The information is not intended to replace medical advice offered by physicians. Please refer to the full text of the Wikiversity medical disclaimer.

This page lists current researches in developing new medications.

The goal of this page is to be a tool see the current state of each research, how it's progressing or if it had failed.

Please help expand it!

Anxiolytic and Sleep Inducers

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Antidepressants

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Cancer Therapy

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Immunology

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  • Dopaminergic System in Autoimmunity[3], Bupropion[4][5][6]
  • Cannabidiol - Inhibits TNF-α[7]

Reduction of nicotine addiction

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See Also

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References

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  1. Oliveira, Daniela Rodrigues de; Todo, Andréia Hatsue; Rêgo, Gizelda Maia; Cerutti, Janete Maria; Cavalheiro, Alberto José; Rando, Daniela Gonçales Galasse; Cerutti, Suzete Maria (July 2018). "Flavones-bound in benzodiazepine site on GABA A receptor: Concomitant anxiolytic-like and cognitive-enhancing effects produced by Isovitexin and 6-C-glycoside-Diosmetin". European Journal of Pharmacology (Elsevier) 831: 77–86. doi:10.1016/j.ejphar.2018.05.004. ISSN 0014-2999. PMID 29738701. 
  2. 2.0 2.1 de Mello Schier, Alexandre R.; de Oliveira Ribeiro, Natalia P.; Coutinho, Danielle S.; Machado, Sergio; Arias-Carrión, Oscar; Crippa, Jose A.; Zuardi, Antonio W.; Nardi, Antonio E. et al. (2014). "Antidepressant-like and anxiolytic-like effects of cannabidiol: a chemical compound of Cannabis sativa". CNS & neurological disorders drug targets 13 (6): 953–960. doi:10.2174/1871527313666140612114838. ISSN 1996-3181. PMID 24923339. https://www.alchimiaweb.com/blogfr/wp-content/uploads/2015/11/2014-Antidepressant-Like-and-Anxiolytic-Like-Effects-of-Cannabidiol.pdf. 
  3. Vidal, PM; Pacheco, R (2019-01-19). "Targeting the Dopaminergic System in Autoimmunity". Journal of Neuroimmune Pharmacology (Springer). doi:10.1007/s11481-019-09834-5. ISSN 1557-1890. PMID 30661214. http://link.springer.com/10.1007/s11481-019-09834-5. 
  4. Kast, RE; Altschuler, EL (Nov 2001). "Remission of Crohn's disease on bupropion". Gastroenterology (Elsevier) 121 (5): 1260–1261. doi:10.1053/gast.2001.29467. ISSN 0016-5085. PMID 11706830. https://linkinghub.elsevier.com/retrieve/pii/S0016508501700212. 
  5. Mosaic, LS. "Why a third of antidepressants are prescribed for something else". CNN. Retrieved 2019-07-06.
  6. Brustolim, D; Ribeiro-dos-Santos, R; Kast, RE; Altschuler, EL; Soares, MBP (Jun 2006). "A new chapter opens in anti-inflammatory treatments:The antidepressant bupropion lowers production of tumor necrosis factor-alpha and interferon-gamma in mice". International Immunopharmacology (Elsevier) 6 (6): 903–907. doi:10.1016/j.intimp.2005.12.007. ISSN 1567-5769. PMID 16644475. https://linkinghub.elsevier.com/retrieve/pii/S1567576906000026. 
  7. Mechoulam, Raphael; Peters, Maximilian; Murillo-Rodriguez, Eric; Hanus, Lumír O. (Aug 2007). "Cannabidiol--recent advances". Chemistry & Biodiversity 4 (8): 1678–1692. doi:10.1002/cbdv.200790147. ISSN 1612-1880. PMID 17712814. https://www.researchgate.net/profile/Eric_Murillo-Rodriguez/publication/6126753_Cannabidiol_-_Recent_Advances/links/5a1f215ea6fdccc6b7fb18d7/Cannabidiol-Recent-Advances.pdf. 
  8. Morgan, Celia J. A.; Das, Ravi K.; Joye, Alyssa; Curran, H. Valerie; Kamboj, Sunjeev K.; Mechoulam, Raphael; Weller, Aron (2013-9). "Cannabidiol reduces cigarette consumption in tobacco smokers: preliminary findings". Addictive Behaviors 38 (9): 2433–2436. doi:10.1016/j.addbeh.2013.03.011. ISSN 1873-6327. PMID 23685330. https://www.alchimiaweb.com/blogfr/wp-content/uploads/2015/11/CBDcigarettes.pdf.