Enzyme inhibition
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This lesson will illustrate the different kinetic scenarios for enzyme inhibition: reversible, irreversible, competitive, non-competitive; and the different strategies for enzyme inhibition: transition state analogues, mechanism-based inhibitors. Examples of enzyme inhibitors for medicinal targets will be illustrated.
Aims
[edit | edit source]By the end of this lesson, you should
- understand different types of enzyme inhibition
- understand strategies for design of enzyme inhibitors