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Progress and Prospects in Parkinson's Research/Symptoms/Catalepsy

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Tireless, timeless , effortless maintenance of postures.

The following references are relevant:-

Azam et al (2010) Design, synthesis and anti-Parkinsonian evaluation of 3-alkyl/aryl-8-(furan-2-yl)thiazolo[5,4-e][1,2,4]triazolo[1,5-c]pyrimidine-2(3H)-thiones against neuroleptic-induced catalepsy and oxidative stress in mice.[1]

Nayebi et al (2010) Buspirone improves 6-hydroxydopamine-induced catalepsy through stimulation of nigral 5-HT(1A) receptors in rats. [2]

Mahmoudi et al (2011) Buspirone improves the anti-cataleptic effect of levodopa in 6-hydroxydopamine-lesioned rats. [3]

Further Research

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Use the following links to query the PubMed, PubMed Central and Google Scholar databases using the Search terms:- Parkinson's_Disease Catalepsy.
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References

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  1. Azam, F.; El-gnidi BA.; Alkskas, I.A. and Ahmed, M.A. (2010) AbstractJ. Enzyme Inhib. Med. Chem. 25 (6) 818 – 826. Design, synthesis and anti-Parkinsonian evaluation of 3-alkyl/aryl-8-(furan-2-yl)thiazolo[5,4-e][1,2,4]triazolo[1,5-c]pyrimidine-2(3H)-thiones against neuroleptic-induced catalepsy and oxidative stress in mice. http://www.ncbi.nlm.nih.gov/pubmed/20429782
  2. Nayebi, A.M.; Rad, S.R.; Saberian, M.; Azimzadeh, S. and Samini, M.(2010) Abstract Pharmacol. Rep. 62 92) 258 – 264 Buspirone improves 6-hydroxydopamine-induced catalepsy through stimulation of nigral 5-HT(1A) receptors in rats. http://www.ncbi.nlm.nih.gov/pubmed/20508280
  3. Mahmoudi, J.; Nayebi, A.M.; Samini, M.; Reyhani-Rad, S.; and Babapour, V. (2011) Abstract Pharmacol. Rep. 63 (4) 908 – 914. Buspirone improves the anti-cataleptic effect of levodopa in 6-hydroxydopamine-lesioned rats. http://www.ncbi.nlm.nih.gov/pubmed/22001978