Progress and Prospects in Parkinson's Research/Symptoms/Aboulia

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Aboulia

Lack of will or initiative

There is an alternative spelling ’Abulia’.

This symptom can come about through trauma or as a result of Deep Brain Stimulation. It can also arise from non-Parkinsonian causes such as degeneration of or surgery upon the frontal lobes.

Common features of aboulia are:-

• Difficulty in initiating and sustaining purposeful movements

• Lack of spontaneous movement

• Reduced spontaneous movement

• Increased response-time to queries

• Passivity

• Reduced emotional responsiveness and spontaneity

• Reduced social interactions

• Reduced interest in usual pastimes

This has been described by:-

Doder et al (1999) Parkinson's syndrome after closed head injury: a single case report

Redgrave et al (2010)Goal-directed and habitual control in the basal ganglia: implications for Parkinson’s disease

Drubach et al (2011)Free Will, Freedom of Choice and Frontotemporal Lobar Degeneration

Further Research

Search the scientific literature (Aboulia)
Literature search: Use the following links to query the PubMed, PubMed Central and Google Scholar databases using the Search terms:- Parkinson's_Disease Aboulia. This will list the latest papers on this topic. You are invited to update this page to reflect such recent results, pointing out their significance. Pubmed (abstracts) Pubmed_Central (Full_Text) Google_Scholar

Search the scientific literature (Abulia)
Literature search: Use the following links to query the PubMed, PubMed Central and Google Scholar databases using the Search terms:- Parkinson's_Disease Abulia. This will list the latest papers on this topic. You are invited to update this page to reflect such recent results, pointing out their significance. Pubmed (abstracts) Pubmed_Central (Full_Text) Google_Scholar