Jump to content

Life expectancy in bipolar disorder

From Wikiversity

This short article by Dan Polansky intends to investigate the following question: what is the change of life expectancy in people with the diagnosis of bipolar disorder compared to the general population?

Relevant snippets from sources found, with comments/reservations:

  • 10-15 years: Yocum 2023: "Several studies have examined life expectancy and Years Per Life Lost (YPLL) for people with BD, and most suggest a 10–15 year reduction in lifespan and a markedly increased, 2–3 times risk of premature death in patients relative to the general population (Chan et al., 2021; Crump et al., 2013a; Kessing et al., 2015; Plana‐Ripoll et al., 2020)."[1]
  • 13 years: Chan 2022: "Eleven and 13 studies were included in the review for life expectancy (n = 96 601) and YPLL (n = 128 989), respectively. Pooled life expectancy was 66.88 years (95% CI 64.47–69.28; I2 = 99.9%, P < 0.001), was higher in women than men (70.51 (95% CI 68.61–72.41) v. 64.59 (95% CI 61.16–68.03); z = 2.00, P = 0.003) and was lowest in Africa. Weighted average YPLL was 12.89 years (95% CI 12.72–13.07), and was greatest in Africa. More YPLL was observed when lifespan was estimated at birth than at other set-age. YPLLs attributable to natural and unnatural deaths were 5.94 years (95% CI 5.81–6.07) and 5.69 years (95% CI 5.59–5.79), respectively."[2]
  • 11-20 and more: Kessing 2015: "Life expectancy in patients with bipolar disorder has been reported to be decreased by 11 to 20 years. [...] Results For the typical male or female patient aged 25 to 45 years, the remaining life expectancy was decreased by 12.0–8.7 years and 10.6–8.3 years, respectively."[3]
  • 9-20 years: University of Oxford 2014: "The average reduction in life expectancy in people with bipolar disorder is between nine and 20 years, while it is 10 to 20 years for schizophrenia, between nine and 24 years for drug and alcohol abuse, and around seven to 11 years for recurrent depression."[4]

References

[edit | edit source]
  1. Comparative mortality risks in two independent bipolar cohorts by Yocum, Friedman, Bertram, Han, McInnis, Dec 2023
  2. Life expectancy and years of potential life lost in bipolar disorder: systematic review and meta-analysis, Chan et al., 2022
  3. Life expectancy in bipolar disorder by Kessing, Vradi, Andersen, 4 Ap 2015
  4. Many mental illnesses reduce life expectancy more than heavy smoking, University of Oxford, 23 May 2014