Osteoarthritis/Quiz

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The formation of hard nobs at the middle finger joints (known as Bouchard's nodes) and at the farther away finger joint (known as Heberden's node) are a common feature of osteoarthritis in the hands. Credit: Drahreg01.

Osteoarthritis is a lecture and part of the gene transcription series.

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Quiz[edit]







  

1

Yes or No, Osteoarthritis is usually considered a degeneration of joint cartilage and the underlying bone, most common from middle age onward.

Yes
No

2

True or False, A cell that makes up the tissue of cartilage is called a chondrocyte.

TRUE
FALSE

3

Chondrocytes, the only cell type present in cartilage, have very low metabolism activity with no ability to repair

.

4

Yes or No, Articular cartilage, once damaged, cannot respond by a usual inflammatory response because it is non-vascularized and non-innervated.

Yes
No

5

Yes or No, Apple, carrot, potato, hazelnut and birch reactivity was transferable in Prausnitz-Küstner test like IgE antibodies.

Yes
No

6

Which of the following is characteristic of the innate immune system?

a non-specific immune system
comprises the cells and mechanisms that defend the host from infection by other organisms in a non-specific manner
triggered after the binding of pathogen-associated molecular patterns (PAMPs)
triggered after the binding of danger-associated molecular patterns (DAMPs) on pattern-recognition receptors (PRRs)
not a driver of the OA process

7

Yes or No, Once degraded, cartilage fragments fall into the joint and contact the synovium.

Yes
No

8

Which of the following are phenomena associated with the synovial membrane?

a thin lining layer within the joint cavity
responsible for maintaining normal joint function and homeostasis
normally highly synthetic fibroblast-like synovial (FLS) cells or synoviocytes
primary source of articular hyaluronic acid and other glycoproteins such as lubricin
uridine diphosphoglucose dehydrogenase, galectin 1 and galectin 3
protein product of chromosome 19 open reading frame 10

9

Yes or No, Any part of the body where two bones join, in most cases allowing that part of the body to be bent or straightened is called a joint.

Yes
No

10

Complete the text:

Synoviocytes participate in complex

and paracrine activation networks with

, lymphocytes, and dendritic cells, which serve to sustain the

and to enhance its destructive

.


Hypotheses[edit]

  1. Osteoarthritis can be reversed by reprogramming gene expression.

See also[edit]

External links[edit]

{{Anthropology resources}}{{Gene project}}{{Medicine resources}}{{Phosphate biochemistry}}