Draft:Orthomolecular medicine

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""Megavitamin therapy" was first coined in 1952 by psychiatrists Humphry Osmond and Abram Hoffer to describe the large dosages of niacin used in the treatment of schizophrenia and mescaline psychosis."[1]

"Megavitamin therapy has become a sub-category of Orthomolecular medicine."[1]

Theoretical orthomolecular medicine[edit]

Def. "the restoration and maintenance of health through the administration of adequate amounts of substances that are normally present in the body"[2] is called orthomolecular medicine.

Vitamin C[edit]

In "a placebo controlled trial for six months, 40 men and women between 60 to 80 years old were administered 500 mg of vitamin C daily. This moderate dose of vitamin C modestly but significantly lowered blood pressure (Fotherby et al 2000). In another study of 514 people, plasma vitamin C levels were inversely related to blood pressure and pulse rate (Bates et al 1998). Elevated blood pressure is a risk factor for age-related atherosclerotic disease."[2]

Coenzyme Q10[edit]

"Coenzyme Q10 (ubiquinone, or coQ10) is an antioxidant that is essential for mitochondrial energy production. It is manufactured in the body, but with aging the amounts are inadequate for optimum health. CoQ10 is essential for the heart muscle, and it helps lower blood pressure, improve congestive heart failure, and protect the brain in degenerative conditions such as Parkinson’s and Alzheimer’s diseases (Morisco et al 1993). Statin drugs significantly lower the production of coQ10. Typical supplemental doses of coQ10 range from 100 mg daily for prevention against high blood pressure to 400 mg for heart disease patients (Munkholm et al 1999)."[2]


"Chromium is a trace mineral that helps to regulate blood sugar and lipid levels. Typical nutritional levels range from 50 mcg to 200 mcg in well nourished people. However, in diabetic patients, high doses of chromium, which are extremely safe, can significantly reduce blood sugar and enhance insulin sensitivity (Anderson et al 1997). When 1000 mcg of chromium were administered to type II diabetics, 90% of them were able to eliminate the need for medication to control blood sugar levels (Anderson 1997). Chromium supplements also lower total cholesterol and increase high density lipoprotein levels."[2]


"Quercetin is a flavonoid that helps to control allergy symptoms of rhinitis and sinusitis. It stabilizes the membranes of mast cells, reducing the release of histamine. It is also helpful in lowering the risk of cataract by inhibiting glycoprotein formation in the lens (Cornish, et al 2002). Typical doses of quercetin are 800 mg to 1200 mg daily."[2]


"The term "Orthomolecular" was first utilized by two-time Nobel Laureate Linus Pauling in 1968 to characterize the treatment of disease with nutrients that were endogenous to the human body. Orthomolecular simply means "correct molecule" which translates into "essential nutrient". Orthomolecular physicians treat disease by varying the dosages of "correct molecules" which are required but not synthesized by the human body. Doctors, adjusting diet, by eliminating junk foods, and prescribing mega dosages of essential vitamins, minerals, trace metals, amino acids, and fats can correct the chemical imbalances of disease."[1]

See also[edit]


  1. 1.0 1.1 1.2 Eric Braverman (1979). "Orthomolecular Medicine and Megavitamin Therapy: Future and Philosophy". Orthomolecular Psychiatry 8 (4): 265-72. http://www.orthomolecular.org/library/jom/1979/pdf/1979-v08n04-p265.pdf. Retrieved 2014-08-20. 
  2. 2.0 2.1 2.2 2.3 2.4 Michael Janson (September 2006). "Orthomolecular medicine: the therapeutic use of dietary supplements for anti-aging". Clinical Interventions in Aging 1 (3): 261-5. PMID 18046879. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2695174/. Retrieved 25 September 2018. 

Further reading[edit]

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