Genetics/12p13.31

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Human chromosome region 12p13.31 region contains six genes: CD69, CLEC2D, CLECL1, KLRB1, LOC374443, OVOS. [1] Deletions of this region of the human chromosome have been linked to multiple myeloma. [2]

References[edit | edit source]

  1. http://t1dbase.org/page/Overview/display/locus_id/257
  2. J Clin Oncol. 2009 September 20; 27(27): 4585–4590. Published online 2009 August 17. doi: 10.1200/JCO.2008.20.6136 PMCID: PMC2754906 Prognostic Significance of Copy-Number Alterations in Multiple Myeloma. Hervé Avet-Loiseau, Cheng Li, Florence Magrangeas, Wilfried Gouraud, Catherine Charbonnel, Jean-Luc Harousseau, Michel Attal, Gerald Marit, Claire Mathiot, Thierry Facon, Philippe Moreau, Kenneth C. Anderson, Loïc Campion, Nikhil C. Munshi, and Stéphane Minvielle