Talk:PD Hot Topics
I suggest we start a list of topics here that could be elaborated into Hot Topics.
- BBC News: "Range of brain diseases could be treated by single drug". http://www.bbc.co.uk/news/health-17952797. Protein misfolding disease cause a similar disruption of the protein translation mechanism which can be 'switched back on'.
- Source: Moreno, Julie A., Helois Radford, Diego Peretti, Joern R. Steinert, Nicholas Verity, Maria Guerra Martin, Mark Halliday, et al. “Sustained Translational Repression by eIF2[agr]-P Mediates Prion Neurodegeneration.” Nature (May 6, 2012). http://www.nature.com/nature/journal/vaop/ncurrent/full/nature11058.html.
What do we Know? (Suggestions for Hot Topics)
The following was added to the resource page by User:Reverett123. I have moved them here and shall explain the reasons for doing this and give as much help as possible on his/her talk page at User_talk:Reverett123
. What Do We Know?
II. Systems Interacting in Parkinson’s Disease
A. Immune System B. Endocrine System C. Gastrointestinal System D. Central Nervous System E. Neurotransmitters, Hormones, and Cytokines
III. The Path of Progression of PD
A. Predisposing Factors B. Initiating Triggers
IV. Ongoing Processes
A. Oxidation B. Excitotoxicity C. Mitochondrial Failure D. Neuronflammation and Microglia E. Stress and the HPA F. Autoimmunity
V. Time Periods Related to PD
A. Preconception B. Prenatal C. Prepuberty D. Puberty E. Young Adult F. Mid-Life G. Senior
VI. External Factors and PD
A. Lipopolysaccharide (LPS) B. Pathogens C. Ultrafine Particulates D. Toxins E. Epigenetics
VII. Internal Factors and PD
A. Alpha-Synuclein B. Blood Brain Barrier C. Circadian Rhythms D. Constipation E. Electrolytes and Ion Channels F. Genetics G. Metabolic Factors and Nutrition
VIII. Treatment, Repair, and Cure
A. Therapeutics B. Neurogenesis C. Symptoms
A. Historical View of PD B. Homeostasis C. Related Disorders D. Rhythmic Disruption